FDA on February 21st issued a “Sources Sought Notice/Request for Information” (RFI) to find organizations with the ability to data mine structured data from the National Library of Medicine’s (NLM) MEDLINE to detect potential drug-adverse event associations.
FDA is looking for an automated and fully auditable program capable of quantitative signal detection where drug-event pairs that occur disproportionately higher than expected frequency are identified. They also are looking for a system that has “drill-down” capability to identify and access original resource materials and able to provide links to other relevant scientific electronic databases.
FDA issued the “Sources Sought Notice/RFI” to hear from qualified small businesses for information but FDA welcomes solutions from all interested parties.
Responses are due March 07, 2012 for the RFI “Systematic Data Mining of the Medical Literature: a Novel Analytic Tool for quantitative Drug-Adverse Event Safety Signal Detection” (FDA-SOL-12-1234567).
For more information, go to www.fbo.gov. For questions, email Christine Rynkiewicz at Christine.rynkiewicz@fda.gov.
