Tuesday, November 17, 2009

NINDS Will Publish RFA

The National Institute of Neurological Disorders and Stroke (NINDS) will issue a Request for Application (RFA) to find applicants to redesign the “Parkinson’s Disease Data Organizing Center” (PD-DOC). There is a need for a resource to collect and share data related to clinical and transactional research on Parkinson’s disease and then to develop a centralized repository of the clinical data from both observational studies and clinical trials.

This resource is needed to:

• Serve as a repository for data from large clinical research studies in Parkinson’s disease, including clinical trials as well as epidemiological and genetic studies. Data is needed from academia, non-profit disease organizations, and industry and needs to include clinical as well as genetic, imaging, and neuropathology data elements

• Link clinical data with other data sets including imaging, pathology, genetic, and biospecimens in an easily searchable format

• Develop a flexible open source web-based data entry system to facilitate the design, implementation, and harmonization of new clinical research studies in Parkinson’s disease

• Serve as a centralized listing of Parkinson’s disease related resources for sample collection, antibodies, and animal models

• Provide outreach to promote data standardization, data sharing, and the usefulness of the PD-DOC resource as well as provide oversight of data access

NINDS anticipates a total budget of $5.5 million for the project for over five years. The RFA is expected to be published in December 2009 or January 2010 and applications will be due April 30, 2010.

For information on Notice (NOT-NS-10-003), email Wendy Galpern, M.D., PhD at galpernw@ninds.nih.gov. Go to http://grants.nih.gov/grants/guide/notice-files/NOT-NS-10-003.html to read the full notice.